【摘要】 目的 探讨重症感染患儿抗生素相关性腹泻(AAD) 的发病及抗生素使用情况。方法 回顾性分析166例重症感染患儿的临床资料， 总结和探讨重症感染患儿AAD的发病率、抗生素使用情况。结果 166例患儿中， 发生 AAD 92 例(55.4%) ； 引发 AAD 的常见抗生素为头孢菌素。AAD患儿年龄、抗生素使用时间、种类、基础疾病与非AAD患儿比较差异均有统计学意义(P<0.05)。结论 重症感染患儿AAD发病率较高， 与年龄、抗生素使用时间、种类、基础疾病相关。

    【关键词】 儿童；重症感染；抗生素相关性腹泻

    【Abstract】 Objective To investigate morbidity and antibiotics application condition for antibiotic-associated diarrhea (AAD) in severe infection children. Methods Clinical data of 166 severe infection children were retrospectively analyzed. Summary and investigation were made on morbidity of AAD in severe infection children and antibiotics application condition. Results Among the 166 children ......